REST/NRSF deficiency impairs autophagy and leads to cellular senescence in neurons

During aging, brain performances decline. Cellular senescence is one of the aging drivers and a key feature of a variety of human age‐related disorders. The transcriptional repressor RE1‐silencing transcription factor (REST) has been associated with aging and higher risk of neurodegenerative disorde...

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Detalles Bibliográficos
Autores principales: Rocchi, Anna, Carminati, Emanuele, De Fusco, Antonio, Kowalska, Jagoda Aleksandra, Floss, Thomas, Benfenati, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520714/
https://www.ncbi.nlm.nih.gov/pubmed/34520100
http://dx.doi.org/10.1111/acel.13471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520714/
https://www.ncbi.nlm.nih.gov/pubmed/34520100
http://dx.doi.org/10.1111/acel.13471

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