Identification of distinct and age‐dependent p16(High) microglia subtypes

Cells expressing high levels of the cyclin‐dependent kinase (CDK)4/6 inhibitor p16 (p16(High)) accumulate in aging tissues and promote multiple age‐related pathologies, including neurodegeneration. Here, we show that the number of p16(High) cells is significantly increased in the central nervous sys...

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Detalles Bibliográficos
Autores principales: Talma, Nynke, Gerrits, Emma, Wang, Boshi, Eggen, Bart J.L., Demaria, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520715/
https://www.ncbi.nlm.nih.gov/pubmed/34598318
http://dx.doi.org/10.1111/acel.13450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520715/
https://www.ncbi.nlm.nih.gov/pubmed/34598318
http://dx.doi.org/10.1111/acel.13450

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