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Identification of distinct and age‐dependent p16(High) microglia subtypes
Cells expressing high levels of the cyclin‐dependent kinase (CDK)4/6 inhibitor p16 (p16(High)) accumulate in aging tissues and promote multiple age‐related pathologies, including neurodegeneration. Here, we show that the number of p16(High) cells is significantly increased in the central nervous sys...
Autores principales: | Talma, Nynke, Gerrits, Emma, Wang, Boshi, Eggen, Bart J.L., Demaria, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520715/ https://www.ncbi.nlm.nih.gov/pubmed/34598318 http://dx.doi.org/10.1111/acel.13450 |
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