Identification of a small molecule SR9009 that activates NRF2 to counteract cellular senescence

The senescence‐associated secretory phenotype (SASP) is a striking characteristic of senescence. Accumulation of SASP factors causes a pro‐inflammatory response linked to chronic disease. Suppressing senescence and SASP represents a strategy to prevent or control senescence‐associated diseases. Here...

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Detalles Bibliográficos
Autores principales: Gao, Li‐Bin, Wang, Ya‐Hong, Liu, Zhi‐Hua, Sun, Yu, Cai, Peng, Jing, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520720/
https://www.ncbi.nlm.nih.gov/pubmed/34587364
http://dx.doi.org/10.1111/acel.13483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520720/
https://www.ncbi.nlm.nih.gov/pubmed/34587364
http://dx.doi.org/10.1111/acel.13483

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