Advanced Maternal Age‐associated SIRT1 Deficiency Compromises Trophoblast Epithelial−Mesenchymal Transition through an Increase in Vimentin Acetylation

Advanced maternal age (AMA) pregnancies are rapidly increasing and are associated with aberrant trophoblast cell function, poor placentation, and unfavorable pregnancy outcomes, presumably due to premature placental senescence. SIRT1 is an NAD(+)‐dependent deacetylase with well‐known antiaging effec...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Liling, Ye, Xuan, Chen, Zhi, Fu, Huijia, Li, Sisi, Xu, Ping, Yu, Jiaxiao, Wen, Li, Gao, Rufei, Fu, Yong, Qi, Hongbo, Kilby, Mark D., Saffery, Richard, Baker, Philip N., Tong, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520724/
https://www.ncbi.nlm.nih.gov/pubmed/34605151
http://dx.doi.org/10.1111/acel.13491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520724/
https://www.ncbi.nlm.nih.gov/pubmed/34605151
http://dx.doi.org/10.1111/acel.13491

Ejemplares similares