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microRNA‐425 loss mediates amyloid plaque microenvironment heterogeneity and promotes neurodegenerative pathologies

Different cellular and molecular changes underlie the pathogenesis of Alzheimer's disease (AD). Among these, neuron‐specific dysregulation is a necessary event for accumulation of classic pathologies including amyloid plaques. Here, we show that AD‐associated pathophysiology including neuronal...

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Detalles Bibliográficos
Autores principales: Hu, Yong‐Bo, Zhang, Yong‐Fang, Ren, Ru‐Jing, Dammer, Eric B., Xie, Xin‐Yi, Chen, Shi‐Wu, Huang, Qiang, Huang, Wan‐Ying, Zhang, Rui, Chen, Hong‐Zhuan, Wang, Hao, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520725/
https://www.ncbi.nlm.nih.gov/pubmed/34510683
http://dx.doi.org/10.1111/acel.13454