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Easy and reliable maximum a posteriori Bayesian estimation of pharmacokinetic parameters with the open‐source R package mapbayr

Pharmacokinetic (PK) parameter estimation is a critical and complex step in the model‐informed precision dosing (MIPD) approach. The mapbayr package was developed to perform maximum a posteriori Bayesian estimation (MAP‐BE) in R from any population PK model coded in mrgsolve. The performances of map...

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Detalles Bibliográficos
Autores principales: Le Louedec, Félicien, Puisset, Florent, Thomas, Fabienne, Chatelut, Étienne, White‐Koning, Mélanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520754/
https://www.ncbi.nlm.nih.gov/pubmed/34342170
http://dx.doi.org/10.1002/psp4.12689