Tumor‐associated macrophages (TAMs)‐derived osteopontin (OPN) upregulates PD‐L1 expression and predicts poor prognosis in non‐small cell lung cancer (NSCLC)

BACKGROUND: Programmed cell death ligand 1 (PD‐L1) is widely known as an immune checkpoint molecule in tumor cells. Osteopontin (OPN) is expressed by both tumor cells and tumor‐associated macrophages (TAMs), and both autocrine and paracrine of OPN are considered to be involved in tumor metastasis, p...

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Detalles Bibliográficos
Autores principales: Li, Yue, Liu, Hailin, Zhao, Yujie, Yue, Dongsheng, Chen, Chen, Li, Chenguang, Zhang, Zhenfa, Wang, Changli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520804/
https://www.ncbi.nlm.nih.gov/pubmed/34423566
http://dx.doi.org/10.1111/1759-7714.14108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520804/
https://www.ncbi.nlm.nih.gov/pubmed/34423566
http://dx.doi.org/10.1111/1759-7714.14108

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