Recent Advances of WEE1 Inhibitors and Statins in Cancers With p53 Mutations

p53 is among the most frequently mutated tumor suppressor genes given its prevalence in >50% of all human cancers. One critical tumor suppression function of p53 is to regulate transcription of downstream genes and maintain genomic stability by inducing the G1/S checkpoint in response to DNA dama...

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Detalles Bibliográficos
Autores principales: Meng, Xiangbing, Gao, Jason Z., Gomendoza, Sean Michael T., Li, John W., Yang, Shujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520942/
https://www.ncbi.nlm.nih.gov/pubmed/34671620
http://dx.doi.org/10.3389/fmed.2021.737951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520942/
https://www.ncbi.nlm.nih.gov/pubmed/34671620
http://dx.doi.org/10.3389/fmed.2021.737951

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