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Recent Advances of WEE1 Inhibitors and Statins in Cancers With p53 Mutations
p53 is among the most frequently mutated tumor suppressor genes given its prevalence in >50% of all human cancers. One critical tumor suppression function of p53 is to regulate transcription of downstream genes and maintain genomic stability by inducing the G1/S checkpoint in response to DNA dama...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520942/ https://www.ncbi.nlm.nih.gov/pubmed/34671620 http://dx.doi.org/10.3389/fmed.2021.737951 |