Deletion of PRAK Mitigates the Mitochondria Function and Suppresses Insulin Signaling in C2C12 Myoblasts Exposed to High Glucose

Background: p38 regulated/activated protein kinase (PRAK) plays a crucial role in modulating cell death and survival. However, the role of PRAK in the regulation of metabolic stress remains unclear. We examined the effects of PRAK on cell survival and mitochondrial function in C2C12 myoblasts in res...

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Detalles Bibliográficos
Autores principales: Zhang, Ling, Wang, Jianguo, Zhao, Yu Tina, Dubielecka, Patrycja, Qin, Gangjian, Zhuang, Shougang, Chin, Eugene Y, Liu, Paul Y, Zhao, Ting C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521062/
https://www.ncbi.nlm.nih.gov/pubmed/34671252
http://dx.doi.org/10.3389/fphar.2021.698714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521062/
https://www.ncbi.nlm.nih.gov/pubmed/34671252
http://dx.doi.org/10.3389/fphar.2021.698714

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