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New Challenges Resulting From the Loss of Function of Na(v)1.4 in Neuromuscular Diseases
The voltage-gated sodium channel Na(v)1.4 is a major actor in the excitability of skeletal myofibers, driving the muscle force in response to nerve stimulation. Supporting further this key role, mutations in SCN4A, the gene encoding the pore-forming α subunit of Na(v)1.4, are responsible for a clini...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521073/ https://www.ncbi.nlm.nih.gov/pubmed/34671263 http://dx.doi.org/10.3389/fphar.2021.751095 |