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Real-time three-dimensional tracking of single vesicles reveals abnormal motion and pools of synaptic vesicles in neurons of Huntington's disease mice

Although defective synaptic transmission was suggested to play a role in neurodegenerative diseases, the dynamics and vesicle pools of synaptic vesicles during neurodegeneration remain elusive. Here, we performed real-time three-dimensional tracking of single synaptic vesicles in cortical neurons fr...

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Detalles Bibliográficos
Autores principales: Chen, Sidong, Yoo, Hanna, Li, Chun Hei, Park, Chungwon, Park, Gyunam, Tan, Li Yang, Jung, Sangyong, Park, Hyokeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521108/
https://www.ncbi.nlm.nih.gov/pubmed/34703988
http://dx.doi.org/10.1016/j.isci.2021.103181