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Real-time three-dimensional tracking of single vesicles reveals abnormal motion and pools of synaptic vesicles in neurons of Huntington's disease mice
Although defective synaptic transmission was suggested to play a role in neurodegenerative diseases, the dynamics and vesicle pools of synaptic vesicles during neurodegeneration remain elusive. Here, we performed real-time three-dimensional tracking of single synaptic vesicles in cortical neurons fr...
Autores principales: | Chen, Sidong, Yoo, Hanna, Li, Chun Hei, Park, Chungwon, Park, Gyunam, Tan, Li Yang, Jung, Sangyong, Park, Hyokeun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521108/ https://www.ncbi.nlm.nih.gov/pubmed/34703988 http://dx.doi.org/10.1016/j.isci.2021.103181 |
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