Metabolism of HSAN1- and T2DM-associated 1-deoxy-sphingolipids inhibits the migration of fibroblasts

Hereditary sensory neuropathy type 1 (HSAN1) is a rare axonopathy, characterized by a progressive loss of sensation (pain, temperature, and vibration), neuropathic pain, and wound healing defects. HSAN1 is caused by several missense mutations in the serine palmitoyltransferase long-chain base subuni...

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Detalles Bibliográficos
Autores principales: Karsai, Gergely, Steiner, Regula, Kaech, Andres, Lone, Museer A., von Eckardstein, Arnold, Hornemann, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521209/
https://www.ncbi.nlm.nih.gov/pubmed/34563520
http://dx.doi.org/10.1016/j.jlr.2021.100122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521209/
https://www.ncbi.nlm.nih.gov/pubmed/34563520
http://dx.doi.org/10.1016/j.jlr.2021.100122

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