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High‐resolution analysis of the conformational transition of pro‐apoptotic Bak at the lipid membrane
Permeabilization of the outer mitochondrial membrane by pore‐forming Bcl2 proteins is a crucial step for the induction of apoptosis. Despite a large set of data suggesting global conformational changes within pro‐apoptotic Bak during pore formation, high‐resolution structural details in a membrane e...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521305/ https://www.ncbi.nlm.nih.gov/pubmed/34523144 http://dx.doi.org/10.15252/embj.2020107159 |