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High‐resolution analysis of the conformational transition of pro‐apoptotic Bak at the lipid membrane

Permeabilization of the outer mitochondrial membrane by pore‐forming Bcl2 proteins is a crucial step for the induction of apoptosis. Despite a large set of data suggesting global conformational changes within pro‐apoptotic Bak during pore formation, high‐resolution structural details in a membrane e...

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Detalles Bibliográficos
Autores principales:	Sperl, Laura E, Rührnößl, Florian, Schiller, Anita, Haslbeck, Martin, Hagn, Franz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521305/ https://www.ncbi.nlm.nih.gov/pubmed/34523144 http://dx.doi.org/10.15252/embj.2020107159

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