CRISPR/Cas9-mediated knockout of PIM3 suppresses tumorigenesis and cancer cell stemness in human hepatoblastoma cells

Hepatoblastoma remains one of the most difficult childhood tumors to treat and is alarmingly understudied. We previously demonstrated that Proviral Insertion site in Maloney murine leukemia virus (PIM) kinases, specifically PIM3, are overexpressed in human hepatoblastoma cells and function to promot...

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Detalles Bibliográficos
Autores principales: Marayati, Raoud, Stafman, Laura L., Williams, Adele P., Bownes, Laura V., Quinn, Colin H., Markert, Hooper R., Easlick, Juliet L., Stewart, Jerry E., Crossman, David K., Mroczek-Musulman, Elizabeth, Beierle, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521561/
https://www.ncbi.nlm.nih.gov/pubmed/33864024
http://dx.doi.org/10.1038/s41417-021-00334-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521561/
https://www.ncbi.nlm.nih.gov/pubmed/33864024
http://dx.doi.org/10.1038/s41417-021-00334-4

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