FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors

Parvalbumin interneurons (PVIs) are affected in many psychiatric disorders including schizophrenia (SCZ), however the mechanism remains unclear. FXR1, a high confident risk gene for SCZ, is indispensable but its role in the brain is largely unknown. We show that deleting FXR1 from PVIs of medial pre...

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Detalles Bibliográficos
Autores principales: Shen, Minjie, Guo, Yu, Dong, Qiping, Gao, Yu, Stockton, Michael E., Li, Meng, Kannan, Sudharsan, Korabelnikov, Tomer, Schoeller, Keegan A., Sirois, Carissa L., Zhou, Chen, Le, Jonathan, Wang, Daifeng, Chang, Qiang, Sun, Qian-Quan, Zhao, Xinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521570/
https://www.ncbi.nlm.nih.gov/pubmed/33863995
http://dx.doi.org/10.1038/s41380-021-01096-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521570/
https://www.ncbi.nlm.nih.gov/pubmed/33863995
http://dx.doi.org/10.1038/s41380-021-01096-z

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