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FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors
Parvalbumin interneurons (PVIs) are affected in many psychiatric disorders including schizophrenia (SCZ), however the mechanism remains unclear. FXR1, a high confident risk gene for SCZ, is indispensable but its role in the brain is largely unknown. We show that deleting FXR1 from PVIs of medial pre...
Autores principales: | Shen, Minjie, Guo, Yu, Dong, Qiping, Gao, Yu, Stockton, Michael E., Li, Meng, Kannan, Sudharsan, Korabelnikov, Tomer, Schoeller, Keegan A., Sirois, Carissa L., Zhou, Chen, Le, Jonathan, Wang, Daifeng, Chang, Qiang, Sun, Qian-Quan, Zhao, Xinyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521570/ https://www.ncbi.nlm.nih.gov/pubmed/33863995 http://dx.doi.org/10.1038/s41380-021-01096-z |
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