Human induced pluripotent stem cell-derived platelets loaded with lapatinib effectively target HER2+ breast cancer metastasis to the brain

Prognosis of patients with HER2+ breast-to-brain-metastasis (BBM) is dismal even after current standard-of-care treatments, including surgical resection, whole-brain radiation, and systemic chemotherapy. Radiation and systemic chemotherapies can also induce cytotoxicity, leading to significant side...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhan, Arunoday, Ansari, Khairul, Chen, Mike Y., Jandial, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521584/
https://www.ncbi.nlm.nih.gov/pubmed/34654856
http://dx.doi.org/10.1038/s41598-021-96351-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521584/
https://www.ncbi.nlm.nih.gov/pubmed/34654856
http://dx.doi.org/10.1038/s41598-021-96351-2

Ejemplares similares