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Human induced pluripotent stem cell-derived platelets loaded with lapatinib effectively target HER2+ breast cancer metastasis to the brain

Prognosis of patients with HER2+ breast-to-brain-metastasis (BBM) is dismal even after current standard-of-care treatments, including surgical resection, whole-brain radiation, and systemic chemotherapy. Radiation and systemic chemotherapies can also induce cytotoxicity, leading to significant side...

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Detalles Bibliográficos
Autores principales:	Bhan, Arunoday, Ansari, Khairul, Chen, Mike Y., Jandial, Rahul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521584/ https://www.ncbi.nlm.nih.gov/pubmed/34654856 http://dx.doi.org/10.1038/s41598-021-96351-2

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