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Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders

Understanding the tissue-specific genetic controls of protein levels is essential to uncover mechanisms of post-transcriptional gene regulation. We generated a genomic atlas of protein levels in three tissues relevant to neurological disorders (brain, cerebrospinal fluid (CSF), and plasma), by profi...

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Detalles Bibliográficos
Autores principales: Yang, Chengran, Farias, Fabiana H.G., Ibanez, Laura, Suhy, Adam, Sadler, Brooke, Fernandez, Maria Victoria, Wang, Fengxian, Bradley, Joseph L., Eiffert, Brett, Bahena, Jorge A., Budde, John P., Li, Zeran, Dube, Umber, Sung, Yun Ju, Mihindukulasuriya, Kathie A., Morris, John C., Fagan, Anne M., Perrin, Richard J., Benitez, Bruno A., Rhinn, Herve, Harari, Oscar, Cruchaga, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521603/
https://www.ncbi.nlm.nih.gov/pubmed/34239129
http://dx.doi.org/10.1038/s41593-021-00886-6