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Structural basis of rotavirus RNA chaperone displacement and RNA annealing

Rotavirus genomes are distributed between 11 distinct RNA molecules, all of which must be selectively copackaged during virus assembly. This likely occurs through sequence-specific RNA interactions facilitated by the RNA chaperone NSP2. Here, we report that NSP2 autoregulates its chaperone activity...

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Detalles Bibliográficos
Autores principales: Bravo, Jack P. K., Bartnik, Kira, Venditti, Luca, Acker, Julia, Gail, Emma H., Colyer, Alice, Davidovich, Chen, Lamb, Don C., Tuma, Roman, Calabrese, Antonio N., Borodavka, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521686/
https://www.ncbi.nlm.nih.gov/pubmed/34615715
http://dx.doi.org/10.1073/pnas.2100198118