Doxycycline sensitizes renal cell carcinoma to chemotherapy by preferentially inhibiting mitochondrial translation

OBJECTIVES: The anti-cancer activity of doxycycline has been reported in many cancers but not renal cell carcinoma (RCC). This study aimed to determine the efficacy of doxycycline alone and in combination with paclitaxel and analyze the underlying mechanism in RCC. METHODS: Proliferation, colony for...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Bo, Ao, Jinsong, Li, Xiaoyan, Yu, Weimin, Yu, Dan, Qiu, Chengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Pre-Clinical Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521774/
https://www.ncbi.nlm.nih.gov/pubmed/34644207
http://dx.doi.org/10.1177/03000605211044368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521774/
https://www.ncbi.nlm.nih.gov/pubmed/34644207
http://dx.doi.org/10.1177/03000605211044368

Ejemplares similares