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Doxycycline sensitizes renal cell carcinoma to chemotherapy by preferentially inhibiting mitochondrial translation
OBJECTIVES: The anti-cancer activity of doxycycline has been reported in many cancers but not renal cell carcinoma (RCC). This study aimed to determine the efficacy of doxycycline alone and in combination with paclitaxel and analyze the underlying mechanism in RCC. METHODS: Proliferation, colony for...
Autores principales: | Wang, Bo, Ao, Jinsong, Li, Xiaoyan, Yu, Weimin, Yu, Dan, Qiu, Chengjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521774/ https://www.ncbi.nlm.nih.gov/pubmed/34644207 http://dx.doi.org/10.1177/03000605211044368 |
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