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Polygenic Risk Scores in Alzheimer's Disease: Current Applications and Future Directions
Genome-wide association studies have identified nearly 40 genome-wide significant single nucleotide polymorphisms (SNPs) which are associated with Alzheimer's Disease (AD). Due to the polygenicity of AD, polygenic risk scores (PRS) have shown high potential for AD risk prediction. PRSs have bee...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521998/ https://www.ncbi.nlm.nih.gov/pubmed/34713027 http://dx.doi.org/10.3389/fdgth.2020.00014 |