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Optimization of sepsis therapy based on patient-specific digital precision diagnostics using next generation sequencing (DigiSep-Trial)—study protocol for a randomized, controlled, interventional, open-label, multicenter trial

BACKGROUND: Sepsis is triggered by an infection and represents one of the greatest challenges of modern intensive care medicine. With regard to a targeted antimicrobial treatment strategy, the earliest possible pathogen detection is of crucial importance. Until now, culture-based detection methods r...

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Detalles Bibliográficos
Autores principales: Brenner, Thorsten, Skarabis, Annabell, Stevens, Philip, Axnick, Jennifer, Haug, Peter, Grumaz, Silke, Bruckner, Thomas, Luntz, Steffen, Witzke, Oliver, Pletz, Mathias W., Ruprecht, Thomas M., Marschall, Ursula, Altin, Sibel, Greiner, Wolfgang, Berger, Marc Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522064/
https://www.ncbi.nlm.nih.gov/pubmed/34663439
http://dx.doi.org/10.1186/s13063-021-05667-x