Characterization of an APP/tau rat model of Alzheimer’s disease by positron emission tomography and immunofluorescent labeling

BACKGROUND: To better understand the etiology and pathomechanisms of Alzheimer’s disease, several transgenic animal models that overexpress human tau or human amyloid-beta (Aβ) have been developed. In the present study, we generated a novel transgenic rat model by cross-breeding amyloid precursor pr...

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Detalles Bibliográficos
Autores principales: Filip, Thomas, Mairinger, Severin, Neddens, Joerg, Sauberer, Michael, Flunkert, Stefanie, Stanek, Johann, Wanek, Thomas, Okamura, Nobuyuki, Langer, Oliver, Hutter-Paier, Birgit, Kuntner, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522096/
https://www.ncbi.nlm.nih.gov/pubmed/34656177
http://dx.doi.org/10.1186/s13195-021-00916-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522096/
https://www.ncbi.nlm.nih.gov/pubmed/34656177
http://dx.doi.org/10.1186/s13195-021-00916-2

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