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Characterization of an APP/tau rat model of Alzheimer’s disease by positron emission tomography and immunofluorescent labeling

BACKGROUND: To better understand the etiology and pathomechanisms of Alzheimer’s disease, several transgenic animal models that overexpress human tau or human amyloid-beta (Aβ) have been developed. In the present study, we generated a novel transgenic rat model by cross-breeding amyloid precursor pr...

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Detalles Bibliográficos
Autores principales:	Filip, Thomas, Mairinger, Severin, Neddens, Joerg, Sauberer, Michael, Flunkert, Stefanie, Stanek, Johann, Wanek, Thomas, Okamura, Nobuyuki, Langer, Oliver, Hutter-Paier, Birgit, Kuntner, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522096/ https://www.ncbi.nlm.nih.gov/pubmed/34656177 http://dx.doi.org/10.1186/s13195-021-00916-2

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