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SETD2-mediated epigenetic regulation of noncanonical Wnt5A during osteoclastogenesis

To define the role of SETD2 in the WNT5a signaling in the context of osteoclastogenesis, we exploited two different models: in vitro osteoclast differentiation, and K/BxN serum-induced arthritis model. We found that SETD2 and WNT5a were upregulated during osteoclast differentiation and after inducti...

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Detalles Bibliográficos
Autores principales: Deb, Moonmoon, Laha, Dipranjan, Maity, Jyotirindra, Das, Hiranmoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522097/
https://www.ncbi.nlm.nih.gov/pubmed/34663428
http://dx.doi.org/10.1186/s13148-021-01125-2