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TBX15/miR-152/KIF2C pathway regulates breast cancer doxorubicin resistance via promoting PKM2 ubiquitination

BACKGROUND: Chemoresistance is a critical risk problem for breast cancer treatment. However, mechanisms by which chemoresistance arises remains to be elucidated. The expression of T-box transcription factor 15 (TBX-15) was found downregulated in some cancer tissues. However, role and mechanism of TB...

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Detalles Bibliográficos
Autores principales: Jiang, Cheng-Fei, Xie, Yun-Xia, Qian, Ying-Chen, Wang, Min, Liu, Ling-Zhi, Shu, Yong-Qian, Bai, Xiao-Ming, Jiang, Bing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522147/
https://www.ncbi.nlm.nih.gov/pubmed/34663310
http://dx.doi.org/10.1186/s12935-021-02235-w