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Adipogenic differentiation was inhibited by downregulation of PPARγ signaling pathway in aging tendon stem/progenitor cells

BACKGROUND: Tendon stem/progenitor cells (TSPCs) play a vital role in tendon repair and regeneration. Previously we found more adipocytes accumulated in the patellar tendon injury sites in aging rats compared with the young ones, of which the mechanism is still unknown. Here, we want to identify whe...

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Detalles Bibliográficos
Autores principales: Lai, Fan, Wang, Jingjing, Tang, Hong, Bian, Xuting, Lu, Kang, He, Gang, Huang, Pan, Liu, Juan, Zhou, Mei, Liu, Jian, Tao, Xu, Tang, Kang-lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522149/
https://www.ncbi.nlm.nih.gov/pubmed/34663381
http://dx.doi.org/10.1186/s13018-021-02720-y