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SUMO1 modification of IGF-1R combining with SNAI2 inhibited osteogenic differentiation of PDLSCs stimulated by high glucose

BACKGROUND: Periodontal disease, an oral disease characterized by loss of alveolar bone and progressive teeth loss, is the sixth major complication of diabetes. It is spreading worldwide as it is difficult to be cured. The insulin-like growth factor 1 receptor (IGF-1R) plays an important role in reg...

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Detalles Bibliográficos
Autores principales: Jiang, Rongrong, Wang, Miao, Shen, Xiaobo, Huang, Shuai, Han, Jianpeng, Li, Lei, Xu, Zhiliang, Jiang, Chengfeng, Zhou, Qiao, Feng, Xingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522165/
https://www.ncbi.nlm.nih.gov/pubmed/34663464
http://dx.doi.org/10.1186/s13287-021-02618-w