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SUMO1 modification of IGF-1R combining with SNAI2 inhibited osteogenic differentiation of PDLSCs stimulated by high glucose
BACKGROUND: Periodontal disease, an oral disease characterized by loss of alveolar bone and progressive teeth loss, is the sixth major complication of diabetes. It is spreading worldwide as it is difficult to be cured. The insulin-like growth factor 1 receptor (IGF-1R) plays an important role in reg...
Autores principales: | Jiang, Rongrong, Wang, Miao, Shen, Xiaobo, Huang, Shuai, Han, Jianpeng, Li, Lei, Xu, Zhiliang, Jiang, Chengfeng, Zhou, Qiao, Feng, Xingmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522165/ https://www.ncbi.nlm.nih.gov/pubmed/34663464 http://dx.doi.org/10.1186/s13287-021-02618-w |
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