TREM2 modulates differential deposition of modified and non-modified Aβ species in extracellular plaques and intraneuronal deposits

Progressive accumulation of Amyloid-β (Aβ) deposits in the brain is a characteristic neuropathological hallmark of Alzheimer’s disease (AD). During disease progression, extracellular Aβ plaques undergo specific changes in their composition by the sequential deposition of different modified Aβ specie...

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Detalles Bibliográficos
Autores principales: Joshi, Pranav, Riffel, Florian, Kumar, Sathish, Villacampa, Nàdia, Theil, Sandra, Parhizkar, Samira, Haass, Christian, Colonna, Marco, Heneka, Michael T., Arzberger, Thomas, Herms, Jochen, Walter, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522217/
https://www.ncbi.nlm.nih.gov/pubmed/34663480
http://dx.doi.org/10.1186/s40478-021-01263-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522217/
https://www.ncbi.nlm.nih.gov/pubmed/34663480
http://dx.doi.org/10.1186/s40478-021-01263-x

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