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TREM2 modulates differential deposition of modified and non-modified Aβ species in extracellular plaques and intraneuronal deposits
Progressive accumulation of Amyloid-β (Aβ) deposits in the brain is a characteristic neuropathological hallmark of Alzheimer’s disease (AD). During disease progression, extracellular Aβ plaques undergo specific changes in their composition by the sequential deposition of different modified Aβ specie...
Autores principales: | Joshi, Pranav, Riffel, Florian, Kumar, Sathish, Villacampa, Nàdia, Theil, Sandra, Parhizkar, Samira, Haass, Christian, Colonna, Marco, Heneka, Michael T., Arzberger, Thomas, Herms, Jochen, Walter, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522217/ https://www.ncbi.nlm.nih.gov/pubmed/34663480 http://dx.doi.org/10.1186/s40478-021-01263-x |
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