Tubular lysosomes harbor active ion gradients and poise macrophages for phagocytosis

Lysosomes adopt dynamic, tubular states that regulate antigen presentation, phagosome resolution, and autophagy. Tubular lysosomes are studied either by inducing autophagy or by activating immune cells, both of which lead to cell states where lysosomal gene expression differs from the resting state....

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Detalles Bibliográficos
Autores principales: Suresh, Bhavyashree, Saminathan, Anand, Chakraborty, Kasturi, Zajac, Matthew, Cui, Chang, Becker, Lev, Krishnan, Yamuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522270/
https://www.ncbi.nlm.nih.gov/pubmed/34607961
http://dx.doi.org/10.1073/pnas.2113174118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522270/
https://www.ncbi.nlm.nih.gov/pubmed/34607961
http://dx.doi.org/10.1073/pnas.2113174118

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