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Unique anticodon loop conformation with the flipped-out wobble nucleotide in the crystal structure of unbound tRNA(Val)

During protein synthesis on ribosome, tRNA recognizes its cognate codon of mRNA through base-pairing with the anticodon. The 5′-end nucleotide of the anticodon is capable of wobble base-pairing, offering a molecular basis for codon degeneracy. The wobble nucleotide is often targeted for post-transcr...

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Detalles Bibliográficos
Autores principales: Jeong, Hyeonju, Kim, Jungwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522699/
https://www.ncbi.nlm.nih.gov/pubmed/34315814
http://dx.doi.org/10.1261/rna.078863.121