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Unique anticodon loop conformation with the flipped-out wobble nucleotide in the crystal structure of unbound tRNA(Val)
During protein synthesis on ribosome, tRNA recognizes its cognate codon of mRNA through base-pairing with the anticodon. The 5′-end nucleotide of the anticodon is capable of wobble base-pairing, offering a molecular basis for codon degeneracy. The wobble nucleotide is often targeted for post-transcr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522699/ https://www.ncbi.nlm.nih.gov/pubmed/34315814 http://dx.doi.org/10.1261/rna.078863.121 |