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Clinical and Mechanistic Characteristics of Current JAK Inhibitors in IBD

Crohn’s disease (CD) and ulcerative colitis (UC) are chronic, immune-mediated diseases of the gastrointestinal (GI) tract. Their etiology is complex and involves immune (eg, cytokines) and nonimmune (eg, environment) mediated contributions, causing inflammatory damage to the GI tract. Though cytokin...

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Detalles Bibliográficos
Autores principales: Pippis, Elleni J, Yacyshyn, Bruce R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522789/
https://www.ncbi.nlm.nih.gov/pubmed/33295611
http://dx.doi.org/10.1093/ibd/izaa318