TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan

Multiple myeloma (MM) is an incurable cancer caused by malignant transformation of plasma cells. Transforming growth factor-β activated kinase 1 (MAP3K7, TAK1) is a major regulator of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and mitogen-activated protein kinase (MAPK) s...

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Detalles Bibliográficos
Autores principales: Håland, Erling, Moen, Ingrid Nyhus, Veidal, Elias, Hella, Hanne, Misund, Kristine, Slørdahl, Tobias S., Starheim, Kristian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522844/
https://www.ncbi.nlm.nih.gov/pubmed/34676048
http://dx.doi.org/10.18632/oncotarget.28073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522844/
https://www.ncbi.nlm.nih.gov/pubmed/34676048
http://dx.doi.org/10.18632/oncotarget.28073

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