The Mutation Responsible for Torsion Dystonia Type 1 Shows the Ability To Stimulate Intracellular Aggregation of Mutant Huntingtin

INTRODUCTION: Torsion dystonia type 1 is the most common form of early-onset primary dystonia. Previous reports have suggested that torsin 1A, a protein mutated in this disease, might function as a chaperone that prevents the toxic aggregation of misfolded polypeptides. THE AIM OF THE STUDY: The aim...

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Detalles Bibliográficos
Autores principales: Jurek, Marta, Obersztyn, Ewa, Milewski, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2018
Materias:
Original articles/Prace oryginalne
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522924/
https://www.ncbi.nlm.nih.gov/pubmed/29641419
http://dx.doi.org/10.34763/devperiodmed.20182201.3338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522924/
https://www.ncbi.nlm.nih.gov/pubmed/29641419
http://dx.doi.org/10.34763/devperiodmed.20182201.3338

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