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The Mutation Responsible for Torsion Dystonia Type 1 Shows the Ability To Stimulate Intracellular Aggregation of Mutant Huntingtin
INTRODUCTION: Torsion dystonia type 1 is the most common form of early-onset primary dystonia. Previous reports have suggested that torsin 1A, a protein mutated in this disease, might function as a chaperone that prevents the toxic aggregation of misfolded polypeptides. THE AIM OF THE STUDY: The aim...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Sciendo
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522924/ https://www.ncbi.nlm.nih.gov/pubmed/29641419 http://dx.doi.org/10.34763/devperiodmed.20182201.3338 |