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Sedation Effects Produced by a Ciprofol Initial Infusion or Bolus Dose Followed by Continuous Maintenance Infusion in Healthy Subjects: A Phase 1 Trial

INTRODUCTION: The effects of continuous infusions of ciprofol on its pharmacodynamic and pharmacokinetic properties and safety profiles in healthy Chinese subjects were evaluated. METHODS: In this open-label, randomized, two-way cross-over study, subjects received initial doses of continuous ciprofo...

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Detalles Bibliográficos
Autores principales: Hu, Chao, Ou, Xiaofeng, Teng, Yi, Shu, Shiqing, Wang, Ying, Zhu, Xiaohong, Kang, Yan, Miao, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523013/
https://www.ncbi.nlm.nih.gov/pubmed/34559359
http://dx.doi.org/10.1007/s12325-021-01914-4