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Sedation Effects Produced by a Ciprofol Initial Infusion or Bolus Dose Followed by Continuous Maintenance Infusion in Healthy Subjects: A Phase 1 Trial
INTRODUCTION: The effects of continuous infusions of ciprofol on its pharmacodynamic and pharmacokinetic properties and safety profiles in healthy Chinese subjects were evaluated. METHODS: In this open-label, randomized, two-way cross-over study, subjects received initial doses of continuous ciprofo...
Autores principales: | Hu, Chao, Ou, Xiaofeng, Teng, Yi, Shu, Shiqing, Wang, Ying, Zhu, Xiaohong, Kang, Yan, Miao, Jia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523013/ https://www.ncbi.nlm.nih.gov/pubmed/34559359 http://dx.doi.org/10.1007/s12325-021-01914-4 |
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