Dopamine, sleep, and neuronal excitability modulate amyloid-β–mediated forgetting in Drosophila

Alzheimer disease (AD) is one of the main causes of age-related dementia and neurodegeneration. However, the onset of the disease and the mechanisms causing cognitive defects are not well understood. Aggregation of amyloidogenic peptides is a pathological hallmark of AD and is assumed to be a centra...

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Detalles Bibliográficos
Autores principales: Kaldun, Jenifer C., Lone, Shahnaz R., Humbert Camps, Ana M., Fritsch, Cornelia, Widmer, Yves F., Stein, Jens V., Tomchik, Seth M., Sprecher, Simon G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523056/
https://www.ncbi.nlm.nih.gov/pubmed/34613972
http://dx.doi.org/10.1371/journal.pbio.3001412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523056/
https://www.ncbi.nlm.nih.gov/pubmed/34613972
http://dx.doi.org/10.1371/journal.pbio.3001412

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