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Dopamine, sleep, and neuronal excitability modulate amyloid-β–mediated forgetting in Drosophila
Alzheimer disease (AD) is one of the main causes of age-related dementia and neurodegeneration. However, the onset of the disease and the mechanisms causing cognitive defects are not well understood. Aggregation of amyloidogenic peptides is a pathological hallmark of AD and is assumed to be a centra...
Autores principales: | Kaldun, Jenifer C., Lone, Shahnaz R., Humbert Camps, Ana M., Fritsch, Cornelia, Widmer, Yves F., Stein, Jens V., Tomchik, Seth M., Sprecher, Simon G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523056/ https://www.ncbi.nlm.nih.gov/pubmed/34613972 http://dx.doi.org/10.1371/journal.pbio.3001412 |
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