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ANGPTL8/Betatrophin Improves Glucose Tolerance in Older Mice and Metabolomic Analysis Reveals Its Role in Insulin Resistance in HepG2 Cells

BACKGROUND: Insulin resistance is a determining factor in the pathophysiology of type 2 diabetes mellitus (T2DM). Angiopoietin-like protein 8 (ANGPTL8, also known as betatrophin), associated with glucose homeostasis and lipid metabolism, has attracted attention. But its mechanism in glucose metaboli...

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Detalles Bibliográficos
Autores principales: Xu, Fangfang, Wang, Nan, Li, Gangqiang, Tian, Dandan, Shi, Xiaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523517/
https://www.ncbi.nlm.nih.gov/pubmed/34703256
http://dx.doi.org/10.2147/DMSO.S330700