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ANGPTL8/Betatrophin Improves Glucose Tolerance in Older Mice and Metabolomic Analysis Reveals Its Role in Insulin Resistance in HepG2 Cells

BACKGROUND: Insulin resistance is a determining factor in the pathophysiology of type 2 diabetes mellitus (T2DM). Angiopoietin-like protein 8 (ANGPTL8, also known as betatrophin), associated with glucose homeostasis and lipid metabolism, has attracted attention. But its mechanism in glucose metaboli...

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Detalles Bibliográficos
Autores principales:	Xu, Fangfang, Wang, Nan, Li, Gangqiang, Tian, Dandan, Shi, Xiaoyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523517/ https://www.ncbi.nlm.nih.gov/pubmed/34703256 http://dx.doi.org/10.2147/DMSO.S330700

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